About 5 results found for searched term "DM-01" (0.056 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7535 | HDM201 | Mdm2 |
| NVP-HDM201; Siremadlin | ||
| HDM201 is a novel, highly potent and selective inhibitor of the p53-Mdm2 interaction with affinity constant for Mdm2 in the picomolar range and a selectivity ratio greater than 10000-fold vs Mdm4. | ||
| M8464 | NDMC101 | Others |
| NDMC101 (HS Cm) is a potent dipeptidyl peptidase-IV (DPPIV) inhibitor in T cells with low cytotoxicity. | ||
| M9956 | Darolutamide | Androgen Receptor |
| ODM-201; BAY-1841788 | ||
| Darolutamide (ODM-201) is a new-generation, potent and selective androgen receptor (AR) inhibitor. | ||
| M11169 | DM-01 | Histone Methyltransferase |
| DM-01 is a potent and selective EZH2 inhibitor that can be used to study diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and SNF5/INI-1/SMARCB1 gene-related solid tumors. | ||
| M28523 | UDM-001651 | PAR |
| UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM). UDM-001651 shows antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP). | ||
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